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Min Ae Lee-Kirsch Selected Research

exodeoxyribonuclease I

1/2019Assessment of Clinical Response to Janus Kinase Inhibition in Patients With Familial Chilblain Lupus and TREX1 Mutation.
4/2015Familial chilblain lupus due to a novel mutation in the exonuclease III domain of 3' repair exonuclease 1 (TREX1).
5/2007A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus.

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Min Ae Lee-Kirsch Research Topics

Disease

6Chilblain lupus 1
01/2019 - 05/2007
6Systemic Lupus Erythematosus (Libman-Sacks Disease)
03/2015 - 09/2007
5Bites and Stings (Sting)
01/2022 - 11/2010
5Brain Diseases (Brain Disorder)
02/2021 - 05/2010
5Virus Diseases (Viral Diseases)
01/2017 - 05/2010
3Disease Progression
01/2022 - 09/2016
3chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature
01/2022 - 10/2021
3Arthritis (Polyarthritis)
08/2017 - 05/2010
3Autoimmune Diseases (Autoimmune Disease)
01/2015 - 10/2006
2Dermatomyositis (Dermatopolymyositis)
01/2021 - 01/2020
2Oral Ulcer (Mouth Ulcer)
08/2017 - 05/2010
1Singleton Merten syndrome
04/2022
1Vascular Skin Diseases
01/2022
1Lung Diseases (Lung Disease)
01/2022
1Neoplasms (Cancer)
01/2020
1Macrophage Activation Syndrome
01/2020
1Pulmonary Alveolar Proteinosis
01/2020
1Cutaneous Lupus Erythematosus
01/2019
1Stroke (Strokes)
08/2017
1deficiency of adenosine deaminase 2
08/2017
1Exanthema (Rash)
08/2017
1Cystic Fibrosis (Mucoviscidosis)
11/2016
1Lymphopenia (Lymphocytopenia)
04/2015
1Multiple Sclerosis
02/2015
1Genomic Instability
11/2014
1Leukoencephalopathies
11/2011
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
07/2011
1Wolfram Syndrome (Syndrome, Wolfram)
07/2011
1HIV Infections (HIV Infection)
11/2010
1Leukopenia
05/2010
1Lymphocytosis
05/2010
1Thrombocytopenia (Thrombopenia)
05/2010
1Chilblains (Chilblain)
08/2008
1Anorexia
08/2008
1Granuloma
08/2007
1Chronic Granulomatous Disease
08/2007
1Arthralgia (Joint Pain)
05/2007
1Bacterial Infections (Bacterial Infection)
10/2006
1Type 3 Maturity-Onset Diabetes of the Young
05/2005
1Type 2 Diabetes Mellitus (MODY)
05/2005
1Type 2 Maturity-Onset Diabetes of the Young
05/2005

Drug/Important Bio-Agent (IBA)

8InterferonsIBA
01/2022 - 11/2010
8Interferon Type IIBA
01/2019 - 11/2010
5DNA (Deoxyribonucleic Acid)IBA
02/2017 - 09/2007
4Antinuclear AntibodiesIBA
08/2017 - 05/2007
3ruxolitinibIBA
04/2022 - 01/2021
3exodeoxyribonuclease IIBA
01/2019 - 05/2007
3Antiviral Agents (Antivirals)IBA
03/2015 - 11/2011
3RNA (Ribonucleic Acid)IBA
11/2014 - 11/2010
2Proteasome Endopeptidase Complex (Proteasome)IBA
01/2022 - 01/2022
2Exonucleases (3' 5' Exonuclease)IBA
04/2015 - 09/2007
2EnzymesIBA
01/2015 - 06/2013
2Ribonucleases (Ribonuclease)IBA
01/2015 - 11/2014
2Phosphotransferases (Kinase)IBA
01/2013 - 11/2010
2Transcription Factors (Transcription Factor)IBA
01/2013 - 11/2010
2Granzymes (Granzyme)IBA
09/2007 - 05/2007
1Janus Kinase 1IBA
01/2022
1src-Family KinasesIBA
01/2022
1CytosineIBA
01/2020
1Interleukin-18 (Interleukin 18)IBA
01/2020
1BESIBA
01/2020
1AdenineFDA LinkGeneric
01/2020
1AutoantibodiesIBA
01/2020
1baricitinibIBA
01/2019
1Janus Kinase InhibitorsIBA
01/2019
1Janus KinasesIBA
01/2019
1Adenosine DeaminaseIBA
08/2017
1Complementary DNA (cDNA)IBA
02/2017
1cyclic guanosine monophosphate-adenosine monophosphateIBA
02/2017
1LigandsIBA
02/2017
1TrypsinogenIBA
11/2016
1Pancreatitis-Associated ProteinsIBA
11/2016
1ran-binding protein 2IBA
09/2016
1exodeoxyribonuclease IIIIBA
04/2015
1RibonucleotidesIBA
11/2014
1Nucleic AcidsIBA
11/2011
1Proteins (Proteins, Gene)FDA Link
11/2011
1CytokinesIBA
11/2011
1Glucose (Dextrose)FDA LinkGeneric
07/2011
1Interferon-alpha (Interferon Alfa)IBA
05/2010
1Anti-Bacterial Agents (Antibiotics)IBA
08/2008
1Calcium Channel Blockers (Blockers, Calcium Channel)IBA
08/2008
1SteroidsIBA
08/2008
1AutoantigensIBA
09/2007
13' Untranslated Regions (3' UTR)IBA
09/2007
1CaspasesIBA
05/2007
1Complement System Proteins (Complement)IBA
10/2006
1GlucokinaseIBA
05/2005

Therapy/Procedure

3Therapeutics
01/2022 - 08/2008
1Hematopoietic Stem Cell Transplantation
10/2021
1Glycemic Control
07/2011
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
08/2007